抗体

基质金属蛋白酶9小鼠单克隆抗体IgG1

BA111271

100微升

279美元

单克隆

小鼠

未共轭

10A1

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

抗体

基质金属蛋白酶9小鼠单克隆抗体IgG1

BA111271-100µl

279美元

100微升

Recombinant protein with Human MMP-9 aa 270-400.

免疫印迹, 免疫细胞化学, 免疫组化, FC

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.(EM1801-22)

单克隆

10A1

SwissProt: P14780 Human

蛋白质G纯化

1*TBS (pH7.4), 1%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

小鼠

人类