抗体

毛细血管扩张性共济失调症突变蛋白重组兔单克隆抗体IgG

BA111433

100微升

279美元

单克隆

domestic rabbit

未共轭

免疫印迹, 免疫组化, 免疫细胞化学

抗体

毛细血管扩张性共济失调症突变蛋白重组兔单克隆抗体IgG

BA111433-100µl

279美元

100微升

重组蛋白

免疫印迹, 免疫细胞化学/IF, 免疫组化

Serine-protein kinase ATM, Ataxia telangiectasia mutated

The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy-termini that is not present in the PI 3- and PI 4-kinases. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiec-tases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction.(ET1606-20)

单克隆

Q13315(人类)

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类