抗体

雄激素受体重组兔单克隆抗体IgG

BA111547

100微升

279美元

单克隆

domestic rabbit

未共轭

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

抗体

雄激素受体重组兔单克隆抗体IgG

BA111547-100µl

279美元

100微升

重组蛋白

免疫印迹, 免疫细胞化学/IF, 免疫组化, FC

Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4

Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and male reproductive physiology. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind the two biologically active androgens, testosterone (T) and dihydrotestosterone (DHT), with high and nearly identical affinities; however, the rates of association and dissociation of T are about three times more rapid than those of DHT. This difference has resulted in speculation as to whether these differences in binding kinetics could account for the different physiological effects of T and DHT. A striking feature of AR is its rapid degradation in the absence of ligand. It is now well established that androgen binding results in an at least six-fold increase in androgen stability and that ligand-induced stabilization of AR is highly androgen- specific.(ET1609-18)

单克隆

P10275(人类)

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类