抗体

磷脂酰肌醇(-3)激酶p85乙重组兔单克隆抗体IgG

BA111557

100微升

279美元

单克隆

domestic rabbit

未共轭

人类, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪

抗体

磷脂酰肌醇(-3)激酶p85乙重组兔单克隆抗体IgG

BA111557-100µl

279美元

100微升

重组蛋白

免疫印迹, 免疫细胞化学/IF, 免疫组化, 免疫沉淀, FC

Phosphatidylinositol 3-kinase regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta

Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110α expression is restricted to white blood cells. It has been shown to bind p85α and p85β, but it apparently does not phosphorylate these subunits. p110α seems to have the capacity to autophosphorylate. p110α does not interact with the p85 subunits. It has been shown to be activated by α and β heterotrimeric G proteins.(ET1609-30)

单克隆

O00459(人类)Q63788(大鼠)

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类, 大鼠