抗体

肾母细胞瘤蛋白重组兔单克隆抗体IgG

BA111648

100微升

279美元

单克隆

domestic rabbit

未共轭

人类, 小鼠

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

抗体

肾母细胞瘤蛋白重组兔单克隆抗体IgG

BA111648-100µl

279美元

100微升

重组蛋白

免疫印迹, 免疫细胞化学/IF, 免疫组化, FC

肾母细胞瘤蛋白, WT33

Wilms' tumor (WT) is an embryonal malignancy of the kidney that affects 1 in 10,000 infants and, like retinoblastoma, is observed in both sporadic and inherited forms. The Wilms' tumor locus has been mapped at chromosome 11p13 as a tumor suppressor gene which encodes a DNA binding protein with four zinc fingers and a glutamine-proline rich amino-terminus. The Wilms' tumor protein (WT1) binds the DNA sequence GCGGGGGCG, a recognition element common to the early growth response (Egr) family of Zn2+ finger transcriptional activators. However, in contrast to Egr transcription factors, WT1 behaves as a transcriptional repressor in transient transfection assays with synthetic promotor constructs.(ET1610-45)

单克隆

P19544(人类)P22561(小鼠)

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类, 小鼠