产品简要
公司名称 :
Bon Opus Biosciences
产品类型 :
抗体
产品名称 :
血管紧张素ii类型2受体重组兔单克隆抗体IgG
目录 :
BA111743
规格 :
100微升
价格 :
279美元
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
产品信息
目录 :
BA111743
fieldType :
抗体
名称 :
血管紧张素ii类型2受体重组兔单克隆抗体IgG
SKU号 :
BA111743-100µl
价格 :
279美元
productOptionDescription1 :
100微升
免疫原 :
重组蛋白
应用摘要 :
免疫印迹, 免疫沉淀
别名 :
类型2血管紧张素Ⅱ受体, 血管紧张素ii类型2受体
背景 :
Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLCγ is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites.(ET1611-41)
Clonarity :
单克隆
登录号 :
P50052(人类)P35374(小鼠)Q3US12(小鼠)P35351(大鼠)
纯化 :
ProA affinity purified
配方 :
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
宿主物种 :
物种活性 :
人类, 小鼠, 大鼠
更多信息或购买 :
公司信息
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
公司总部: 美国
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

Every customer is our VIP:

Flat rate charge for gene synthesis, recombinant protein production
  • Guaranteed quality
  • Flexible and care
  • Fast turnaround time
  • Affordable cost


Our reagents, your discovery!