抗体

雌激素受体β重组兔单克隆抗体IgG

BA111970

100微升

279美元

单克隆

domestic rabbit

未共轭

抗体

雌激素受体β重组兔单克隆抗体IgG

BA111970-100µl

279美元

100微升

重组蛋白

免疫印迹

Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2

Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functional characteristics.(ET1701-69)

单克隆

Q92731(人类)

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类