抗体

转铁蛋白受体(CD71)重组兔单克隆抗体IgG

BA112009

100微升

279美元

单克隆

domestic rabbit

未共轭

JF0956

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫沉淀, 流式细胞仪

抗体

转铁蛋白受体(CD71)重组兔单克隆抗体IgG

BA112009-100µl

279美元

100微升

重组蛋白

免疫印迹, 免疫组化, 免疫沉淀, FC

转铁蛋白受体蛋白1, T9, p90, CD_antigen: CD71

CD71, also known as the transferrin receptor (TFR), is a type II membrane glycoprotein that exists as a disulfide-linked homodimer of two identical subunits. CD71 binds to two molecules of transferrin and a serum iron-transport protein, and directs the cellular uptake of iron via receptor-mediated endocytosis. CD71 is expressed, typically at high levels, on all proliferating cells, reticulocytes and erythroid precursors. It is not expressed on resting leukocytes, but is upregulated upon activation of lymphocytes, monocytes and macrophages. CD71 is also found on most dividing cells and on brain endothelium. A second transferrin receptor, TFR2, also mediates the uptake of transferrin-bound iron. TFR2 is a two-subunit homodimer and is highly expressed in liver as well as in hepatocytes and erythroid precursors. Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3), an iron overloading disorder predominant in Caucasians.(ET1702-06)

单克隆

JF0956

P02786(人类)Q62351(小鼠)Q99376(大鼠)

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类, 小鼠, 大鼠