抗体

磷酸化PKC甲(T638)重组兔单克隆抗体IgG

BA112020

100微升

279美元

单克隆

domestic rabbit

未共轭

JF0964

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀

抗体

磷酸化PKC甲(T638)重组兔单克隆抗体IgG

BA112020-100µl

279美元

100微升

Synthetic phospho-Peptide corresponding to residues surrounding Thr638 of human PKC alpha.

免疫印迹, 免疫细胞化学/IF, 免疫组化, 免疫沉淀

蛋白激酶Cα类型

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor-promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into many different isoforms (α, βI, βII, γ, δ, ε, ζ, η, θ, λ/ι, μ and ν). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca 2+ . On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.(ET1702-17)

单克隆

JF0964

P17252(人类)P20444(小鼠)P05696(大鼠)

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类, 小鼠, 大鼠