抗体

芳香酶重组兔单克隆抗体IgG

BA112179

100微升

279美元

单克隆

domestic rabbit

未共轭

JM10-68

人类, 大鼠

免疫印迹, 免疫沉淀

抗体

芳香酶重组兔单克隆抗体IgG

BA112179-100µl

279美元

100微升

重组蛋白

免疫印迹, 免疫沉淀

芳香酶, CYPXIX, 细胞色素P-450AROM, 细胞色素P450 19A1, 雌激素合成酶

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. P450 enzymes can be classified, based on their sequence similarities, into distinct subfamilies, which include CYP1A and CYP2A. Other P450 family members include CYP19, also designated aromatase (P450arom), which catalyzes the conversion of C19 steroids to estrogens in various tissues, including placenta, gonads, adipose tissue, skin and brain. CYP19 expression is controlled by hormonally regulated promoters in different tissues and increased CYP19 activity is associated with familial gynecomastia. Also, a polymorphic allele of CYP19 (repeat (TTTA)12) is present in a majority of breast cancer patients. P450 cholesterol 7α-hydroxylase, CYP7A1, is the rate-limiting enzyme of bile acid synthesis in the liver, and its expression is mediated by the bile acid receptor FXR. CYP27A1 catalyzes vitamin D3 25-hydroxylation and is localized to the mitochondria in kidney and liver.(ET1703-77)

单克隆

JM10-68

P11511(人类)P22443(大鼠)

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类, 大鼠