抗体

CD27重组兔单克隆抗体IgG

BA112545

100微升

279美元

单克隆

domestic rabbit

未共轭

JB40-98

人类, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

抗体

CD27重组兔单克隆抗体IgG

BA112545-100µl

279美元

100微升

Intracellular domain corresponding to Human CD27.

免疫印迹, 免疫细胞化学, 免疫组化, FC

CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD_antigen: CD27

The tumor necrosis factor (TNF) receptor family is composed of several type I integral membrane glycoproteins that exhibit homology in their cysteine-rich extracellular domains. Members of this family include FAS, OX40, CD27 and CD30. Ligands for these receptors are often type II transmembrane glycoproteins, as is the case for CD27 and CD30. CD27 is a homodimeric lymphocyte-specific surface antigen present on T and B lymphocytes. Activation of the CD3 complex via the T cell receptor for antigen leads to an increase in CD27 expression. Together, CD27 and its ligand, CD27L, generate co-stimulatory signals required for complete T cell activation. CD30 is a surface marker for neoplastic cells of the Hodgkin's lymphoma and related hematologic malignancies. CD30L has been shown to enhance the proliferation of the Hodgkin's cell line HDLM-2, but exerts antiproliferative effects on large cell anaplastic lymphoma cell lines.(ET7107-73)

单克隆

JB40-98

P26842(人类)

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类, 大鼠