产品简要
公司名称 :
Bon Opus Biosciences
产品类型 :
ELISA/assay
产品名称 :
人类白细胞介素13(IL-13)酶联免疫吸附试剂盒
目录 :
BE010047
规格 :
96 well
价格 :
473.00美元
更多信息或购买 :
产品信息
目录代码 :
BE010047
产品名称 :
人类白细胞介素13(IL-13)酶联免疫吸附试剂盒
产品类型 :
酶联免疫吸附试剂盒
规格 :
96 well
标价 :
473.00美元
登录号 :
P35225
背景 :
IL-13 is a 10kD unglycosylated protein, secreted mainly by activated T helper 2 cells. IL-13 binds to IL-4Rα in addition to IL-13Rα1 and IL-13Rα2. And the function of IL-13 partially overlaps with IL-4. Both IL-4 and IL-13 link to signal transducer and activator of transcription 6 (STAT6) through the receptor activation. IL-13 can induce B-cell proliferation and IgE classs switching. However, IL-13 is less competent in this function comparing with IL-4. Unlike IL-4, IL-13 does not play an important role in hematopoietic cell shift, such as naïve T helper 0 differentiation to T helper 2. IL-I3 signaling is significant in inducing physiological changes to non-immuno cells in parasitized organs. For example, IL-13 induces enhanced gut contractions and glycoprotein hypersecretion which lead to the detachment of helminthes from gut wall. Eggs produced by Schistosoma mansoni can be limited inside granulomas formed through IL-13 induced cell changes. To organisms resided inside cells, IL-13 seemed to inhibit the clearance from host cell through antagonizing Th1 responses. IL-13 is also associated with many features of the allergic airway diseases, including mucus hypersecretion, goblet metaplasia, chemokine induction and recruitment of effector cells. All of them contribute to airway obstruction. Polymorphisms in IL-13 gene have been found to link to increased eosinophil count, serum total IgE and high risk of asthma.
储存 :
存放在4°C。 不冻结
更多信息或购买 :
公司信息
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
公司总部: 美国
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

Every customer is our VIP:

Flat rate charge for gene synthesis, recombinant protein production
  • Guaranteed quality
  • Flexible and care
  • Fast turnaround time
  • Affordable cost


Our reagents, your discovery!