蛋白

重组人类钙粘蛋白1/E钙粘蛋白/CDH1(C多聚组氨酸)

BP099

50微克;500微克

重组人类钙粘蛋白1/E钙粘蛋白/CDH1(C多聚组氨酸)

蛋白

P12830

50微克;500微克

150

BP099-50微克

50微克;500微克

Recombinant Human Cadherin-1 is produced by Human 293 Cells. The target gene encoding Q23-A709 is expressed with a 8His tag at the C terminus.

人类293细胞

E-Cadherin is a calcium-dependent cell adhesion glycoprotein that belongs to the cadherin family. E-Cadherin is expressed in non-neural epithelial tissues. It tends to interact with each other in a homophilic manner in connecting cells. E-Cadherin clusters are critical components of adherent junctions between epithelial cells and act in the formation and maintenance of the epithelial cell barrier. E-Cadherin is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells and has a potent invasive suppressor role. E-Cadherin loss contributes to cancer metastasis. The extracellular E-Cadherin N-terminal domain can be cleaved by several proteases and is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.

Less than 0.1 EU/ug

Lyophilized frum a 0.2 um filtered solution of PBS, pH7.2

Ambient

钙粘蛋白1;CDH1;CAM 120/80;E钙粘蛋白;CD324