蛋白

重组人类粘着斑蛋白/VCL

BP208

10微克;50微克;500微克;1毫克

150美元

重组人类粘着斑蛋白/VCL

蛋白

P18206-2

10微克;50微克;500微克;1毫克

150

BP208-10微克

150美元

10微克;50微克;500微克;1毫克

Recombinant Human Vinculin is produced by our E.coli expression system and the target gene encoding Met1-Gln1066 is expressed.

大肠杆菌

Vinculin is a cytoskeletal protein that is a member of the vinculin/α-Catenin family. Vinculin is allocated mainly at cell-cell junctions and cell-extracellular matrix (ECM) adhesion. Vinculin is an actin-binding protein that detects the mechanical properties of the extracellular environment. It plays an important role in coupling, transmiting, transduceing, and regulating mechanical force between the cytoskeleton and adhesion receptors. Vinculin can form two structural states, an open (active) and closed (inactive) state, decided by conformational interaction between its head and tail domains. Vinculin also takes part in the mechano-chemical signal transmission of cells by binding to a variety of focal adhesion or cytoskeletal proteins, and is essential in cell's adhesion, extension, motion, proliferation and survival.

Less than 1 EU/ug

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH7.2

Ambient

Vinculin; Metavinculin; VCL