蛋白

重组人类真核生物肽起始因子4e结合蛋白1/EIF4EBP1(N-6His)

C200

10微克;50微克;500微克;1毫克

重组蛋白

重组人类真核生物肽起始因子4e结合蛋白1/EIF4EBP1(N-6His)

C200-10微克

10微克;50微克;500微克;1毫克

Q13541

Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) is a number of the eIF4E-binding protein family. 4EBP1 regulates eIF4E activity by preventing its assembly into the eIF4F complex. 4EBP1 mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. Non-phosphorylated 4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E. 4EBP1 is phosphorylated in response to various signals including insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. 4EBP1 has a role in progression of breast neoplasms through cell signaling.

大肠杆菌

Ambient

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Eukaryotic Translation Initiation Factor 4E-Binding Protein 1, 4E-BP1, eIF4E-Binding Protein 1, Phosphorylated Heat- and Acid-Stable Protein Regulated by Insulin 1, PHAS-I, EIF4EBP1