蛋白

Recombinant Human Endoglin/CD105 (N-Trx, 6His)

CG65

10微克;50微克;500微克;1毫克

重组蛋白

Recombinant Human Endoglin/CD105 (N-Trx, 6His)

重组蛋白

CG65-10微克

10微克;50微克;500微克;1毫克

P17813

Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins and/or other RGD receptors. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1), which is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations.

大肠杆菌

Dry Ice/ice packs

Supplied as a 0.2 μm filtered solution of 20mM PB，150mM NaCl,pH7.4.

Endoglin, END, CD105, ENG