蛋白

Recombinant Mouse PDGF R α/PDGFRA/CD140a (C-Fc)

CM96

10微克;50微克;500微克;1毫克

重组蛋白

Recombinant Mouse PDGF R α/PDGFRA/CD140a (C-Fc)

重组蛋白

CM96-10微克

10微克;50微克;500微克;1毫克

P26618

Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-α and -β. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα, -ββ and -αβ. PDGFRα and PDGFRβ are members of the class III RTK family. Inappropriate PDGFRα and PDGFRβ signaling has been linked to a number of proliferative disorders.

人类细胞

Ambient

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, Platelet-derived growth factor alpha receptor, CD140a, PDGFRA