产品简要
公司名称 :
Bon Opus Biosciences
产品类型 :
蛋白
产品名称 :
Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)
目录 :
CP69
规格 :
10微克;50微克;500微克;1毫克
价格 :
95美元
更多信息或购买 :
产品信息
目录 :
CP69
类型 :
重组蛋白
名称 :
Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)
collection :
酶;重组蛋白
SKU号 :
CP69-10微克
价格 :
95美元
productOptionDescription1 :
10微克;50微克;500微克;1毫克
登录号 :
P04626
背景 :
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and differentiation. HER2 has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on. HER2 is activated by dimerization and not activated by EGF, TGF-alpha and amphiregulin. Interaction with PTK6 increases its intrinsic kinase activity.It is heterodimer with EGFR, ERBB3 and ERBB4. HER2 associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. It implicated in transcriptional activation of CDKN1A and the function of the protein involves STAT3 and SRC. And also it involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth.
Expression :
人类细胞
包装 :
Ambient
配方 :
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
别名 :
Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; Proto-oncogene Neu;Tyrosine kinase-type cell surface receptor HER2; ERBB2;MLN19;NGL;TKR1
更多信息或购买 :
公司信息
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
公司总部: 美国
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

Every customer is our VIP:

Flat rate charge for gene synthesis, recombinant protein production
  • Guaranteed quality
  • Flexible and care
  • Fast turnaround time
  • Affordable cost


Our reagents, your discovery!