抗体

抗磷酸化p53(S378)TP53抗体

A00001S378

100微升

380美元

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定

抗磷酸化p53(S378)TP53抗体

380美元

100微升

多克隆

兔

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定

免疫印迹1:500-1:2000酶联免疫吸附测定1:20000

Boster Bio Anti-Phospho-p53 (S378) TP53 Antibody catalog # A00001S378. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

1毫克/毫升

TP53

P04637

Synthesized peptide derived from human p53 around the phosphorylation site of S378.

液体

液体PBS含50% 甘油, 0.5% BSA和0.02% 叠氮化钠

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

IgG

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

蛋白S100-B

蛋白S100-B;S-100蛋白乙链;S-100蛋白亚基乙;S100钙结合蛋白B;S100钙结合蛋白B;

蛋白S100-B

10713分子量

Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

细胞质

Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.