产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗磷酸化p53(T18)TP53抗体
目录 :
A00001T18
规格 :
100微升
价格 :
380美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
多克隆
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定
产品信息
SKU号 :
A00001T18
产品名称 :
抗磷酸化p53(T18)TP53抗体
价格 :
380美元
规格 :
100微升
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 小鼠, 大鼠
应用(s) :
免疫印迹, 酶联免疫吸附测定
应用细节 :
免疫印迹1:500-1:2000酶联免疫吸附测定1:20000
描述 :
Boster Bio Anti-Phospho-p53 (T18) TP53 Antibody catalog # A00001T18. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
浓度 :
1毫克/毫升
基因名称 :
TP53
UniProt数据库编号 :
P04637
免疫原 :
Synthesized peptide derived from human p53 around the phosphorylation site of T18.
形式 :
液体
Contents :
液体PBS含50% 甘油, 0.5% BSA和0.02% 叠氮化钠
纯化 :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
抗体亚型 :
IgG
储存 :
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
基因全称 :
胶原酶3
同义词 :
胶原酶3;3.4。 24.-;基质金属蛋白酶13;基质金属蛋白酶-13;MMP13;
蛋白名 :
胶原酶3
分子量 :
53820分子量
Protein Function :
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
Subcellular Localization :
Secreted, extracellular space, extracellular matrix
组织特异性 :
Detected in fetal cartilage and calvaria, in chondrocytes of hypertrophic cartilage in vertebrae and in the dorsal end of ribs undergoing ossification, as well as in osteoblasts and periosteal cells below the inner periosteal region of ossified ribs. Detected in chondrocytes from in joint cartilage that have been treated with TNF and IL1B, but not in untreated chondrocytes. Detected in T lymphocytes. Detected in breast carcinoma tissue.
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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