产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗NOD2(Card15)抗体
目录 :
A00087
规格 :
50微升
价格 :
299美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫沉淀
更多信息或购买 :
图像
图像 1 :
Formalin-fixed, paraffin-embedded normal human colon stained for NOD2 expression using primary antibody dilution ratio of 1:2000. A, tissue core from a colon tissue microarray. A1, high magnification of A. Hematoxylin-eosin counterstain.
图像 2 :
Western blot analysis of NOD2 using primary antibody dilution ratio of 1:2000. 30 ug total protein was loaded per lane. Samples from human tumor cell lines: PPC-1 (prostate carcinoma), NCI-H226 and NCI-H332M (lung carcinoma), SF-268 (glioblastoma), UO-31 and A498 (renal/kidney carcinoma), SK-MEL-5 and SK-MEL-28 (melanoma), and MCF-7 (breast carcinoma). Lymphoma is from a cell line generated from a tumor growing in nude mice following injection of primary human lymphoma cells.
产品信息
SKU号 :
A00087
状态 :
Enabled
名称 :
抗NOD2(Card15)抗体
目录名称 :
一抗, 多克隆抗体, 免疫组化免疫细胞化学IF抗体
基因名称 :
NOD2
价格 :
299美元
price various sizes :
50 ul / $299 50 ul+Free HRP Secondary BA1054 / $299 50 ul+Free Biotin Secondary BA1003 / $299
克隆性 :
多克隆
浓度 :
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
共轭标签 :
No
contents :
50 ul sera
描述 :
Polyclonal antibody for NOD2 detection. Host: Rabbit.Size: 100 ug. Tested applications: IP. Reactive species: Human. NOD2 information: Molecular Weight: 115283 MW; Subcellular Localization: Cytoplasm . Membrane . Basolateral cell membrane ; Tissue Specificity: Monocytes-specific.
short description :
Rabbit IgG Polyclonal antibody for NOD2 detection. Tested with WB, IHC, IP in Human.
规格 :
50微升
sample size available :
No sample size available
UniProt数据库编号 :
Q9HC29
宿主 :
兔
免疫原 :
A合成肽,来自人类NOD2/CARD15(氨基酸582-600 LGFLVRAKGVVPGSTAPLE)
形式 :
Liquid
储存 :
Store the antibody at 4 C, stable for 6 months. For long-term storage, store at -20 C. Avoid repeated freeze and thaw cycles.
应用细节 :
WB, 1:1000-1:2000. IHC (paraffin), 1:1000-1:5000. IHC (frozen), Users should optimize. IP, 1:50-1:200.
应用 :
免疫沉淀, 免疫组化, 免疫印迹
反应物种 :
人类
图像标记 :
Formalin-fixed, paraffin-embedded normal human colon stained for NOD2 expression using primary antibody dilution ratio of 1:2000. A, tissue core from a colon tissue microarray. A1, high magnification of A. Hematoxylin-eosin counterstain. Western blot analysis of NOD2 using primary antibody dilution ratio of 1:2000. 30 ug total protein was loaded per lane. Samples from human tumor cell lines: PPC-1 (prostate carcinoma), NCI-H226 and NCI-H332M (lung carcinoma), SF-268 (glioblastoma), UO-31 and A498 (renal/kidney carcinoma), SK-MEL-5 and SK-MEL-28 (melanoma), and MCF-7 (breast carcinoma). Lymphoma is from a cell line generated from a tumor growing in nude mice following injection of primary human lymphoma cells.
competitor equivalent skus :
sc 23587 sc 30199 sc 56168
研究种类 :
Apoptosis, Caspases Etc, Cell Biology, Intracellular
同义词 :
Nucleotide-binding oligomerization domain-containing protein 2;Caspase recruitment domain-containing protein 15;Inflammatory bowel disease protein 1;NOD2;CARD15, IBD1;
基因全称 :
Nucleotide-binding oligomerization domain-containing protein 2
分子量 :
115283分子量
protein function :
Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed:18511561).
subcellular localization :
Cytoplasm . Membrane . Basolateral cell membrane .
组织特异性 :
Monocytes-specific.
蛋白名 :
Nucleotide-binding oligomerization domain-containing protein 2
更新 :
2/6/19 22:57
更多信息或购买 :
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn925.485.4527
公司总部: 美国
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