抗体

抗颗粒酶B GZMB抗体

A00353

100µl

299美元

多克隆

domestic rabbit

未共轭

人类, 大鼠

免疫印迹, 免疫组化

抗颗粒酶B GZMB抗体

299美元

100µl

多克隆

兔

人类, 小鼠, 大鼠

免疫印迹, 免疫组化

免疫印迹, 1:500-1:3000.免疫组化, 1:50-1:100

Boster Bio Anti-Granzyme B GZMB Antibody catalog # A00353. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

GZMB

P10144

Synthesized peptide derived from human Granzyme B.

液体

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免疫原亲和纯化

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

颗粒酶B

Granzyme B; 3.4.21.79; C11; CTLA-1; Cathepsin G-like 1; CTSGL1; Cytotoxic T-lymphocyte proteinase 2; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; HLP; SECT; T-cell serine protease 1-3E; GZMB; CGL1, CSPB, CTLA1, GRB;

27716分子量

This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Cytoplasmic granule. Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells.

Adaptive Immunity, Apoptosis, Cell Biology, Immunology, Innate Immunity, Nk Cells, T Cells