抗体

抗HNF4甲/丙(K127)HNF4A抗体

A00389

100微升

512美元

多克隆

domestic rabbit

未共轭

多克隆

免疫印迹, 免疫组化

抗HNF4甲/丙(K127)HNF4A抗体

512美元

100微升

多克隆

兔

人类, 小鼠, 大鼠

免疫印迹, 免疫组化

WB: 1:500~1:1000 IHC: 1:50~1:200

Boster Bio Anti-HNF4 Alpha / Gamma (K127) HNF4A Antibody catalog # A00389. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

HNF4A

P41235

液体

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

甘油醛3脱氢酶

Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; 1.2.1.12; Peptidyl-cysteine S-nitrosylase GAPDH; 2.6.99.-; GAPDH; GAPD; CDABP0047, OK/SW-cl.12;

甘油醛3脱氢酶

36053分子量

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D- glyceroyl phosphate. Component of the GAIT (gamma interferon- activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

细胞质, 细胞质基质

Widely expressed, with the highest expression in lung, spleen and thymus.