抗体

抗HNF4甲(磷酸化S313)HNF4A抗体

A00389S313

100微升

547美元

多克隆

domestic rabbit

未共轭

多克隆

抗HNF4甲(磷酸化S313)HNF4A抗体

547美元

100微升

多克隆

兔

人类, 小鼠, 大鼠

免疫组化

IHC: 1:50~1:200

Boster Bio Anti-HNF4 Alpha (phospho-S313) HNF4A Antibody catalog # A00389S313. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

HNF4A

P41235

液体

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

端粒酶逆转录酶

端粒酶逆转录酶;2.7。 7.49

端粒酶逆转录酶

126997分子量

Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA- dependent extension of 3'-chromosomal termini with the 6- nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.

Nucleus, nucleolus

Expressed at a high level in thymocyte subpopulations, at an intermediate level in tonsil T-lymphocytes, and at a low to undetectable level in peripheral blood T- lymphocytes.