抗ID2抗体 | 武汉博士德生物工程有限公司 A00417 产品信息

产品简要

公司名称 :

武汉博士德生物工程有限公司

产品类型 :

抗体

产品名称 :

抗ID2抗体

A00417

规格 :

100微升

价格 :

269美元

克隆性 :

多克隆

宿主 :

兔

共轭标签 :

nonconjugated

反应物种 :

人类, 小鼠, 大鼠

应用 :

免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片

更多信息或购买 :

武汉博士德生物工程有限公司产品网页

产品信息

SKU号 :

A00417

名称 :

抗ID2抗体

价格 :

269美元

免疫原 :

KLH合成多肽共轭人GIG8/ID2 33-82氨基酸

形式 :

Liquid

宿主 :

兔

contents :

缓冲液溶液含1% BSA, 50% 甘油和0.09% 叠氮化钠

纯化 :

蛋白质A纯化

克隆性 :

多克隆

描述 :

Rabbit IgG polyclonal antibody for DNA-binding protein inhibitor ID-2 (ID2) detection. Tested with WB, IHC-P, IF in Human, Mouse, Rat.

规格 :

100微升

反应物种 :

人类;小鼠;大鼠

应用 :

IF;免疫组化-P;免疫印迹

基因全称 :

DNA-binding protein inhibitor ID-2

基因名称 :

ID2

protein function :

Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.

研究种类 :

epigenetics and nuclear signaling transcription domain families hlh / leucine zipper hlh stem cells signaling pathways tgf beta nuclear

储存 :

At -20 for one year. After reconstitution, at 4 for one month. It can also be aliquotted and stored frozen at -20 for a longer time.Avoid repeated freezing and thawing.

subcellular localization :

Cytoplasm . Nucleus .

同义词 :

DNA-binding protein inhibitor ID-2;Class B basic helix-loop-helix protein 26;bHLHb26;Inhibitor of DNA binding 2;Inhibitor of differentiation 2;ID2;BHLHB26;

组织特异性 :

Highly expressed in early fetal tissues, including those of the central nervous system.

UniProt数据库编号 :

Q02363

更多信息或购买 :

武汉博士德生物工程有限公司产品网页

公司信息