抗体

抗AR(G207)抗体

A00542-1

100微升

512美元

多克隆

domestic rabbit

未共轭

抗AR(G207)抗体

512美元

100微升

多克隆

兔

人类

免疫组化

IHC: 1:50~1:200

Boster Bio Anti-AR (G207) Antibody catalog # A00542-1. Tested in IHC applications. This antibody reacts with Human.

AR

P10275

液体

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

MHC class I polypeptide-related sequence A

MHC class I polypeptide-related sequence A; MIC-A; MICA

MHC class I polypeptide-related sequence A

42915分子量

Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T- cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

细胞膜

Widely expressed with the exception of the central nervous system where it is absent. Expressed predominantly in gastric epithelium and also in monocytes, keratinocytes, endothelial cells, fibroblasts and in the outer layer of Hassal's corpuscles within the medulla of normal thymus. In skin, expressed mainly in the keratin layers, basal cells, ducts and follicles. Also expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In thyomas, overexpressed in cortical and medullar epithelial cells. Tumors expressing MICA display increased levels of gamma delta T-cells.