产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-Human Neurexin 1 DyLight® 488 conjugated NRXN1 Antibody
目录 :
A01490-Dyl488
规格 :
50 ug/vial
价格 :
415美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
DyLight488
反应物种 :
人类
应用 :
流式细胞仪
图像
图像 1 :
武汉博士德生物工程有限公司 A01490-Dyl488 图像 1
Boster Kit Box
产品信息
SKU号 :
A01490-Dyl488
产品名称 :
Anti-Human Neurexin 1 DyLight® 488 conjugated NRXN1 Antibody
价格 :
415美元
规格 :
50 ug/vial
克隆性 :
多克隆
宿主 :
共轭标签 :
DyLight系列染料®488
反应物种 :
人类
应用(s) :
流式细胞仪
应用细节 :
流式细胞仪, 1-3μg/1x10^6细胞
描述 :
Boster Bio Anti-Human Neurexin 1 DyLight® 488 conjugated NRXN1 Antibody catalog # A01490-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
浓度 :
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
基因名称 :
NRXN1
UniProt数据库编号 :
P58400
免疫原 :
E. coli-derived human Neurexin 1 recombinant protein (Position: D141-E294).
形式 :
液体
Contents :
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
交叉活性 :
No cross reactivity with other proteins.
储存 :
At 2-8?C for one year from date of receipt. Protect from light. Do not freeze.
基因全称 :
neurexin 1
同义词 :
Neurexin-1-beta; Neurexin I-beta; NRXN1
Protein Function :
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity).
Subcellular Localization :
Cell membrane; Localized on the pre- synaptic membrane.
背景 :
Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca (2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.
研究种类 :
Adapters, Axonal Guidance Proteins, Cell Adhesion Proteins, Cell Type Marker, Growth And Development, Membrane Proteins, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction, Synapse Marker, Transmembrane
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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