产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-PDE5A Antibody Picoband™
目录 :
A02490-2
规格 :
100μg/vial
价格 :
315美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化
图像
图像 1 :
武汉博士德生物工程有限公司 A02490-2 图像 1
Western blot analysis of PDE5A expression in rat lung extract (lane 1) and PANC-1 whole cell lysates(lane 2). PDE5A at 100KD was detected using rabbit anti- PDE5A Antigen Affinity purified polyclonal antibody (Catalog # A02490-2) at 0.5 ug/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002).
图像 2 :
武汉博士德生物工程有限公司 A02490-2 图像 2
PDE5A was detected in paraffin-embedded sections of human thyroid cancer tissues using rabbit anti- PDE5A Antigen Affinity purified polyclonal antibody (Catalog # A02490-2) at 1 ug/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022).
产品信息
SKU号 :
A02490-2
产品名称 :
Anti-PDE5A Antibody Picoband™
价格 :
315美元
规格 :
100μg/vial
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 大鼠
应用(s) :
免疫组化, 免疫印迹
应用细节 :
Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, By Heat. Western blot, 0.1-0.5µg/ml, Human, Rat.
应用注释 :
Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-PDE5A Antibody Picoband™ catalog # A02490-2. Tested in IHC, WB applications. This antibody reacts with Human, Rat.
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
基因名称 :
PDE5A
UniProt数据库编号 :
O76074
免疫原 :
different from the related mouse sequence by eight amino acids.
QKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWF
AERVH),
A synthetic peptide corresponding to a sequence at the N-terminus of human PDE5A (20-63aa
形式 :
冻干
Contents :
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
纯化 :
免疫原亲和纯化
交叉活性 :
No cross reactivity with other proteins
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
基因全称 :
cGMP-specific 3',5'-cyclic phosphodiesterase
同义词 :
cGMP-specific 3',5'-cyclic phosphodiesterase; 3.1.4.35 ; cGMP-binding cGMP-specific phosphodiesterase; CGB-PDE; PDE5A; PDE5;
蛋白名 :
cGMP-specific 3',5'-cyclic phosphodiesterase
分子量 :
99985分子量
Protein Function :
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'- GMP (PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide-generated cGMP (PubMed:15489334).
组织特异性 :
Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
背景 :
cGMP-specific phosphodiesterase type 5 is an enzyme from the phosphodiesterase class. It is found in various tissues, most prominently the corpus cavernosum and the retina. It has also been recently discovered to play a vital role in the cardiovascular system. Furthermore, PDE5A also plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This PDE5A gene is mapped to 4q26.
研究种类 :
Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Heart Disease, Hypertrophy, Metabolism, Metabolism Processes, Nucleotide Messenger, Oxidative Stress, Pathways And Processes, Redox Metabolism, Response To Hypoxia, Second Messenger, Signal Transduction
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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