抗体

Anti-Claudin 7/CLDN-7 Antibody Picoband™

A03851-3

100µg/vial

315美元

多克隆

domestic rabbit

未共轭

多克隆

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片

Anti-Claudin 7/CLDN-7 Antibody Picoband™

315美元

100µg/vial

多克隆

兔

人类

酶联免疫吸附测定, 流式细胞仪, IF, 免疫组化-P, 免疫细胞化学, 免疫印迹

Western blot, 0.1-0.25 μg/ml, Human. Immunohistochemistry (Paraffin-embedded Section), 1-2µg/ml, Human. Immunocytochemistry/Immunofluorescence, 5 µg/ml, Human. Immunofluorescence, 5 µg/ml, Human. Flow Cytometry, 1-3μg/1x10^6 cells, Human. Direct ELISA, 0.1-0.5µg/ml, Human.

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Boster Bio Anti-Claudin 7/CLDN-7 Antibody Picoband™ catalog # A03851-3. Tested in ELISA, Flow Cytometry, IF, IHC-P, ICC, WB applications. This antibody reacts with Human.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

CLDN7

O95471

E.coli-derived human Claudin 7/CLDN-7 recombinant protein (Position: F92-V211).

冻干

Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

免疫原亲和纯化

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

SOCS3 (Suppressor of cytokine signaling 3) is a protein that in humans is encoded by the SOCS3 gene. SOCS3 is transiently expressed by multiple cell lineages within the immune system and functions predominantly as a negative regulator of cytokines that activate the JAK-STAT3 pathway. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. For signaling of IL-6, Epo, GCSF and Leptin, binding of SOCS3 to the respective cytokine receptor has been found to be crucial for the inhibitory function of SOCS3. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.