抗体

抗IV型胶原抗体生物素共轭标签

B02908

100微克

329美元

多克隆

兔

生物素

Enabled

抗IV型胶原抗体生物素共轭标签

一抗, 多克隆抗体, 免疫组化免疫细胞化学IF抗体

COL4A4

329美元

100ug / $329 100ug+Free HRP Secondary BA1054 / $329 100ug+Free Biotin Secondary BA1003 / $329

多克隆

1.0 mg/mL by UV absorbance at 280 nm

生物素

Polyclonal antibody for COL4A4 detection. Host: Rabbit.Size: 100ug. Tested applications: IHC. Reactive species: Human. COL4A4 information: Molecular Weight: 164038 MW; Subcellular Localization: Secreted, extracellular space, extracellular matrix, basement membrane . Colocalizes with COL4A4 and COL4A5 in GBM, tubular basement membrane (TBM) and synaptic basal lamina (BL); Tissue Specificity: Alpha 3 and alpha 4 type IV collagens are colocalized and present in kidney, eye, basement membranes of lens capsule, cochlea, lung, skeletal muscle, aorta, synaptic fibers, fetal kidney and fetal lung. PubMed:8083201 reports similar levels of expression of alpha 3 and alpha 4 type IV collagens in kidney, but PubMed:7523402 reports that in kidney levels of alpha 3 type IV collagen are significantly lower than those of alpha 4 type IV collagen. Highest levels of expression of alpha 4 type IV collagen are detected in kidney, calvaria, neuroretina and cardiac muscle. Lower levels of expression are observed in brain, lung and thymus, and no expression is detected in choroid plexus, liver, adrenal, pancreas, ileum or skin.

Anti-Collagen Type IV Antibody Biotin Conjugated tested for IHC in Human.

100微克

25ug for $99, contact us for details

P53420

兔

冻干

No cross reactivity with other proteins.

ImmunoPrecipitation: 1:100, human, bovine. Immunohistochemistry: 1:1, 000 - 1:5, 000, human, bovine

免疫组化

人类

Bovine, Mammalian

Collagen IV was detected in paraffin-embedded sections of human kidney tissue (Left) and human liver tissue (Right) using rabbit anti-Collagen Type IV biotin conjugated polyclonal antibody (Catalog # B02908) at 10 µg/mL.

sc 167524 sc 167523

Cancer, Collagen, Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Invasion/Microenvironment, Mesenchymal Stem Cells, Signal Transduction, Stem Cells

胶原甲4(IV)链;COL4A4;

胶原甲4(IV)链

164038分子量

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.

Secreted, extracellular space, extracellular matrix, basement membrane . Colocalizes with COL4A4 and COL4A5 in GBM, tubular basement membrane (TBM) and synaptic basal lamina (BL).

Alpha 3 and alpha 4 type IV collagens are colocalized and present in kidney, eye, basement membranes of lens capsule, cochlea, lung, skeletal muscle, aorta, synaptic fibers, fetal kidney and fetal lung. PubMed:8083201 reports similar levels of expression of alpha 3 and alpha 4 type IV collagens in kidney, but PubMed:7523402 reports that in kidney levels of alpha 3 type IV collagen are significantly lower than those of alpha 4 type IV collagen. Highest levels of expression of alpha 4 type IV collagen are detected in kidney, calvaria, neuroretina and cardiac muscle. Lower levels of expression are observed in brain, lung and thymus, and no expression is detected in choroid plexus, liver, adrenal, pancreas, ileum or skin.

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