产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Human Amphiregulin(AR) / AREG ELISA Kit PicoKine®
目录 :
EK0304
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
更多信息或购买 :
文章摘录数: 2
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图像
图像 1 :
Human Amphiregulin(AR) PicoKine ELISA Kit standard curve
产品信息
SKU号 :
EK0304
产品名称 :
Human Amphiregulin(AR) / AREG ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
描述 :
Human Amphiregulin (AR) / AREG ELISA Kit PicoKine® (96 Tests). Quantitate Human AREG in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva and human milk. Sensitivity: 10pg/ml.
反应物种 :
人类
应用 :
酶联免疫吸附测定
基因名称 :
AREG
UniProt数据库编号 :
P15514
免疫原 :
Expression system for standard: E.coli; Immunogen sequence: S101-K198
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
15.6 pg/ml - 1,000 pg/ml
敏感性 :
<10 pg/ml
样品类型 :
cell culture supernatants, serum, plasma (heparin, EDTA), saliva and human milk
Capture/Detection Antibodies :
单克隆抗体来自小鼠, 多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
Amphiregulin
同义词 :
Amphiregulin;AR;Colorectum cell-derived growth factor;CRDGF;AREG;SDGF;AREGB;
蛋白名 :
Amphiregulin
分子量 :
27895分子量
Protein Function :
Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Subcellular Localization :
Membrane; Single-pass membrane protein.
Sequence Similarities :
Belongs to the amphiregulin family.
背景 :
Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor family. This gene is mapped to 4q13.1. It is an autocrine growth factor as well as a mitogen forastrocytes, Schwann cells, fibroblasts. Amphiregulin is related to toepidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor to promote the growth of normal epithelial cells. It has been found that transgene integration and subsequent expression of Amphiregulin in basal keratinocytes correlated with a psoriasis-like skin phenotype, and its expression was increased in parallel with typical Th2 cytokines. Amphiregulin is also an important paracrine mediator of estrogen function specifically required for puberty-induced ductal elongation but not for any earlier or later developmental stages, and it can enhance resistance to nematodes.
研究种类 :
Cancer, Growth Factors, Growth Factors/Hormones, Signal Transduction
更多信息或购买 :
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn925.485.4527
公司总部: 美国
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