产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Monkey primate BDNF ELISA Kit PicoKine®
目录 :
EK0307-PR
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
文章摘录数: 1
参考文献
Koeva Y, Sivkov S, Akabaliev V, Ivanova R, Deneva T, Grozlekova L, et al. Brain-derived neurotrophic factor and its serum levels in schizophrenic patients. Folia Med (Plovdiv). 2014;56:20-3 pubmed
产品信息
SKU号 :
EK0307-PR
产品名称 :
Monkey primate BDNF ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
描述 :
Monkey primate BDNF ELISA Kit PicoKine® (96 Tests). Quantitate Monkey BDNF in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 15pg/ml.
反应物种 :
Monkey
应用 :
酶联免疫吸附测定
基因名称 :
BDNF
UniProt数据库编号 :
P23560
免疫原 :
Expression system for standard: NS0; Immunogen sequence: H129-R247
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
31.2 pg/ml - 2,000 pg/ml
敏感性 :
<15 pg/ml
样品类型 :
cell culture supernatants, serum and plasma (heparin, EDTA, citrate)
Capture/Detection Antibodies :
单克隆抗体来自小鼠, 单克隆抗体来自小鼠
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
脑源性神经营养因子
同义词 :
Brain-derived neurotrophic factor;BDNF;Abrineurin;BDNF;
蛋白名 :
脑源性神经营养因子
分子量 :
27818分子量
Protein Function :
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Subcellular Localization :
Secreted.
组织特异性 :
Brain. Highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. Also expressed in heart, lung, skeletal muscle, testis, prostate and placenta.
Sequence Similarities :
Belongs to the NGF-beta family.
背景 :
Brain-derived neurotrophic factor (BDNF) is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is a secreted protein with the molecular weight of 27.8kDa, consisting of 247 amino acids. It is known to promote neuronal survival and differentiation. BDNF shares substantial amino acid sequence identity with nerve growth factor (NGF). BDNF and neurotrophin-3 (NT-3) are two recently cloned neurotrophic factors that are homologous to NGF. mRNA products of the BDNF and NT-3 genes are detected in the adult monkey primate brain, suggesting that these proteins are involved in the maintenance of the adult nervous system. BDNF and other neurotrophins are critically involved in long-term potentiation (LTP). BDNF-mediated LTP is induced postsynaptically. BDNF has trophic effects on serotonergic (5-HT) neurons in the central nervous system. BDNF has an essential maintenance function in the regulation of anxiety-related behavior and in food intake through central mediators in both the basal and fasted state. It plays a role in treating breathing disorders such as respiratory insufficiency after spinal injury. The mature form of BDNF is identical in all mammals examined, and the gene encoding monkey primate BDNF to chromosome 11, band p13.
研究种类 :
Alzheimer'S Disease, Atherosclerosis, Cardiovascular, Diabetes, Diabetes Associated, Growth And Development, Metabolism, Neurodegenerative Disease, Neurology Process, Neuroscience, Obesity
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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