产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Human Eotaxin / CCL11 ELISA Kit PicoKine®
目录 :
EK0329
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
文章摘录数: 2
参考文献
Wang L, Chien C, Tai C, Chiang F, Chen J. Vitamin D decreases the secretion of eotaxin and RANTES in nasal polyp fibroblasts derived from Taiwanese patients with chronic rhinosinusitis with nasal polyps. Kaohsiung J Med Sci. 2015;31:63-9 pubmed 出版商
Chen W, Paulus B, Shu D, Wilson -, Chadwick V. Increased serum levels of eotaxin in patients with inflammatory bowel disease. Scand J Gastroenterol. 2001;36:515-20 pubmed
图像
图像 1 :
武汉博士德生物工程有限公司 EK0329 图像 1
Human Eotaxin PicoKine ELISA Kit standard curve
产品信息
SKU号 :
EK0329
产品名称 :
Human Eotaxin / CCL11 ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
描述 :
Human Eotaxin / CCL11 ELISA Kit PicoKine® (96 Tests). Quantitate Human CCL11 in cell culture supernatants, serum and plasma (citrate, EDTA). Sensitivity: 2pg/ml.
反应物种 :
人类
应用 :
酶联免疫吸附测定
基因名称 :
CCL11
UniProt数据库编号 :
P51671
免疫原 :
Expression system for standard: E.coli; Immunogen sequence: G24-P97
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
15.6 pg/ml - 1,000 pg/ml
敏感性 :
<2 pg/ml
样品类型 :
cell culture supernatants, serum and plasma (citrate, EDTA)
Capture/Detection Antibodies :
单克隆抗体来自小鼠, 多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
Eotaxin
同义词 :
Eotaxin;C-C motif chemokine 11;Eosinophil chemotactic protein;Small-inducible cytokine A11;CCL11;SCYA11;
蛋白名 :
Eotaxin
分子量 :
10732分子量
Protein Function :
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
Subcellular Localization :
Secreted.
Sequence Similarities :
Belongs to the intercrine beta (chemokine CC) family.
背景 :
Eotaxin, also known as CCL11, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. Eotaxin is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. The deduced mature protein sequence is 66% identical to human monocyte chemoattractant protein-1, and 60% identical to guinea pig eotaxin. Recombinant human eotaxin produced in insect cells induces a calcium flux response in normal human eosinophils, but not in neutrophils or monocytes. The human eotaxin gene is cloned and found to be 61.8 and 63.2% identical at the amino acid level to guinea pig and mouse eotaxin.
研究种类 :
Chemokines, Immunology, Innate Immunity
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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