ELISA/assay

Mouse Eotaxin-1 ELISA Kit PicoKine®

EK0330

96 wells/kit, with removable strips.

369美元

Mouse Eotaxin-1 ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Mouse Eotaxin-1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ccl11 in cell culture supernatants, serum and plasma (citrate, EDTA). Sensitivity: 1pg/ml.

小鼠

酶联免疫吸附测定

CCL11

P48298

Expression system for standard: E.coli; Immunogen sequence: H24-P97

There is no detectable cross-reactivity with other relevant proteins.

15.6 pg/ml - 1,000 pg/ml

<1 pg/ml

cell culture supernatants, serum and plasma (citrate, EDTA)

单克隆抗体来自大鼠, 多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Eotaxin

Eotaxin;C-C motif chemokine 11;Eosinophil chemotactic protein;Small-inducible cytokine A11;Ccl11;Scya11;

Eotaxin

10893分子量

In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils.

Secreted.

Expressed constitutively in the thymus. Expression inducible in the lung (type I alveolar epithelial cells), intestine, heart, spleen, kidney.

Eotaxin, also known as CCL11, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. Eotaxin is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. The deduced mature protein sequence is 66% identical to human monocyte chemoattractant protein-1, and 60% identical to guinea pig eotaxin.

Chemokines, Immunology, Innate Immunity