ELISA/assay

Mouse FAS/Cd95 ELISA Kit PicoKine®

EK0336

96 wells/kit, with removable strips.

369美元

Mouse FAS/Cd95 ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Mouse FAS/Cd95 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Fas in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 3pg/ml.

小鼠

酶联免疫吸附测定

肿瘤坏死因子受体超家族成员6

Q8C350

Expression system for standard: NS0; Immunogen sequence: Q22-R169

There is no detectable cross-reactivity with other relevant proteins.

31.2 pg/ml - 2,000 pg/ml

<3 pg/ml

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

单克隆抗体来自大鼠, 多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Fas cell surface death receptor

Tumor necrosis factor receptor superfamily member 6 ;Fas ;

Tumor necrosis factor receptor superfamily member 6

7116分子量

Fas, also known as APO-1, CD95 and TNFRSF6, is a member of the nerve growth factor (NGF)/tumour necrosis factor (TNF) receptor superfamily and mediates apoptosis. The nucleotide sequence of the cDNAs reveales that the molecule coding for the Fas antigen determinant is a 319 amino acid polypeptide with a single transmembrane domain. The extracellular domain is rich in cysteine residue, and shows a similarity to that of human tumor necrosis factor receptors, human nerve growth factor receptor, and human B cell antigen CD40. The APO-1 antigen as defined by the mouse monoclonal antibody anti-APO-1 is previously found to be expressed on the cell surface of activated human T and B lymphocytes and a variety of malignant human lymphoid cell lines. The APO-1 antigen is found to be a membrane glycoprotein of 48-kDa. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. Fas can play a role as an inducer of both neurite growth in vitro and accelerates recovery after nerve injury in vivo.

Adaptive Immunity, Apoptosis, Autoimmune, Cell Biology, Cytokines, Hematopoietic Progenitors, Immune System Diseases, Immunology, Innate Immunity, Lymphoid, Stem Cells, T Lymphocytic Lineage, Tnf Superfamily