产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Monkey primate FGF1/Fgf Acidic ELISA Kit PicoKine®
目录 :
EK0339-PR
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
产品信息
SKU号 :
EK0339-PR
产品名称 :
Monkey primate FGF1/Fgf Acidic ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
描述 :
Monkey primate FGF1/Fgf Acidic ELISA Kit PicoKine® (96 Tests). Quantitate Monkey FGF1 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.
反应物种 :
Monkey
应用 :
酶联免疫吸附测定
基因名称 :
成纤维细胞生长因子-1
UniProt数据库编号 :
P05230
免疫原 :
Expression system for standard: E.coli; Immunogen sequence: A2-D155
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
31.2 pg/ml - 2,000 pg/ml
敏感性 :
<10 pg/ml
样品类型 :
cell culture supernatants, serum and plasma (heparin, EDTA)
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
成纤维细胞生长因子
同义词 :
Fibroblast growth factor 1;FGF-1;Acidic fibroblast growth factor;aFGF;Endothelial cell growth factor;ECGF;Heparin-binding growth factor 1;HBGF-1;FGF1;FGFA;
蛋白名 :
成纤维细胞生长因子
分子量 :
17460分子量
Protein Function :
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
Subcellular Localization :
Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu (2+) ions and S100A13. Secreted in a complex with SYT1 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as LRRC59.
组织特异性 :
Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle.
背景 :
Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. The FGF1 gene was mapped to chromosome 5q31.3-q33.2 by in situ hybridization.
研究种类 :
Angiogenesis, Cancer, Cardiovascular, Growth Factors, Growth Factors/Hormones, Signal Transduction
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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