产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Human ICAM-1 / CD54 ELISA Kit PicoKine®
目录 :
EK0370
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
图像
图像 1 :
武汉博士德生物工程有限公司 EK0370 图像 1
Human ICAM-1 PicoKine ELISA Kit standard curve
产品信息
SKU号 :
EK0370
产品名称 :
Human ICAM-1 / CD54 ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
描述 :
Human ICAM-1 / CD54 ELISA Kit PicoKine® (96 Tests). Quantitate Human ICAM1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.
反应物种 :
人类
应用 :
酶联免疫吸附测定
基因名称 :
细胞间粘附分子 1
UniProt数据库编号 :
P05362
免疫原 :
Expression system for standard: NS0; Immunogen sequence: Q28-E480
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
156 pg/ml - 10,000 pg/ml
敏感性 :
<10 pg/ml
样品类型 :
cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)
Capture/Detection Antibodies :
单克隆抗体来自小鼠, 多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
细胞间粘附分子1
同义词 :
Intercellular adhesion molecule 1;ICAM-1;Major group rhinovirus receptor;CD54;ICAM1;
蛋白名 :
细胞间粘附分子1
分子量 :
57825分子量
Protein Function :
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Subcellular Localization :
Membrane; Single-pass type I membrane protein.
Sequence Similarities :
Belongs to the immunoglobulin superfamily. ICAM family.
背景 :
Intercellular adhesion molecule-1 (ICAM-1) is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for lymphocyte function-associated (LFA) antigens, a beta 2 leukocyte integrin. The normal function of human intercellular adhesion molecule-1 (ICAM-1) is to provide adhesion between endothelial cells and leukocytes after injury or stress. ICAM-1 binds to leukocyte function-associated antigen (LFA-1) or macrophage-1 antigen (Mac-1). ICAM-1 is found on leukocytes, fibroblasts, epithelial cells and endothelial cells and its expression is regulated by inflammatory cytokines. ICAM-1 has a tissue distribution similar to that of the major histocompatibility complex class II antigens and is likely to play a role in inflammatory responses.1
研究种类 :
Adaptive Immunity, Atherosclerosis, Cardiovascular, Cell Adhesion Molecules, Cell Type Markers, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells, T Lymphocytic Lineage, Vascular Inflammation
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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