产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Mouse IGF-2 ELISA Kit PicoKine®
目录 :
EK0381
规格 :
96 wells/kit, with removable strips.
价格 :
400美元
文章摘录数: 1
参考文献
Regué L, Ji F, Flicker D, Kramer D, Pierce W, Davidoff T, et al. IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism. Mol Cell Biol. 2019;39: pubmed 出版商
图像
图像 1 :
武汉博士德生物工程有限公司 EK0381 图像 1
Mouse IGF-2 PicoKine ELISA Kit standard curve
产品信息
SKU号 :
EK0381
产品名称 :
Mouse IGF-2 ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
400美元
描述 :
Mouse IGF-2 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Igf2 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 5pg/ml.
反应物种 :
小鼠
应用 :
酶联免疫吸附测定
基因名称 :
IGF2
UniProt数据库编号 :
P09535
免疫原 :
Expression system for standard: E.coli; Immunogen sequence: A25-E91
交叉活性 :
There is no detectable cross-reactivity with IGF-1.
试验范围 :
62.5 pg/ml - 4,000 pg/ml
敏感性 :
<5 pg/ml
样品类型 :
cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)
Capture/Detection Antibodies :
单克隆抗体来自大鼠, 多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
胰岛素样生长因子ii
同义词 :
Insulin-like growth factor II;IGF-II;Multiplication-stimulating polypeptide;Insulin-like growth factor II;Preptin;Igf2;Igf-2;
蛋白名 :
胰岛素样生长因子ii
分子量 :
20030分子量
Protein Function :
The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.
Subcellular Localization :
Secreted.
背景 :
Insulin-like growth factor II is also known as somatomedin A. IGF-2 is a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is paternally expressed in the fetus and placenta. IGF-II is a mitogen for many cell types and an important modulator of muscle growth and differentiation. IGF-II gene is prevalently expressed during prenatal development and its gene activity is regulated by genomic imprinting, in that the allele inherited from the father is active and the allele inherited from the mother is inactive in most normal tissues. IGF-II appears to be induced by placental lactogen during prenatal development. It is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in breast cancers, are components of a developmental pathway in the mammary gland.
研究种类 :
信号转导
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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