ELISA/assay

Human IGFBP2 ELISA Kit PicoKine®

EK0384

96 wells/kit, with removable strips.

369美元

Human IGFBP2 ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Human IGFBP2 ELISA Kit PicoKine® (96 Tests). Quantitate Human IGFBP2 in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 10pg/ml.

人类

酶联免疫吸附测定

IGFBP2

P18065

Expression system for standard: NS0; Immunogen sequence: E40-Q328

There is no detectable cross-reactivity with other relevant proteins.

62.5 pg/ml - 4,000 pg/ml

<10 pg/ml

cell culture supernatants, serum, plasma (heparin, EDTA) and urine

单克隆抗体来自小鼠, 多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

胰岛素样生长因子结合蛋白2

胰岛素样生长因子结合蛋白2;IBP-2;IGF结合蛋白2;IGFBP-2;IGFBP2;BP2, IBP2;

胰岛素样生长因子结合蛋白2

34814分子量

Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Secreted.

含1 IGFBP N末端区域

Insulin-like growth factor-binding protein 2 (IGFBP2), also called IBP2, is a protein that in humans is encoded by the IGFBP2 gene. It is mapped to 2q35. By structural analysis, it showed that the IGFBP2 gene consists of 4 exons with 3 introns of lengths 27.0, 1.0, and 1.9 kb. IGFBP2 secreted by metastatic cells recruits endothelia by modulating IGF1 mediated activation of the IGF type-I receptor on endothelial cells. The IGFBP2/IGF1/IGF1R and GAS6/MERTK signaling pathways are regulators of cancer-mediated endothelial recruitment.

Cancer, Extracellular Matrix, Growth Factors, Growth Factors/Hormones, Invasion/Microenvironment, Signal Transduction