产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Monkey primate NGF/NGF Beta ELISA Kit PicoKine®
目录 :
EK0469-PR
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
文章摘录数: 1
参考文献
Li Y, Yang C, Lei L, Wu K, Yang P, Xiao W. Serum nerve grow factor and brain-derived neurotrophic factor profiles in Sjögren's syndrome concomitant with interstitial lung disease. Clin Rheumatol. 2014;33:1161-4 pubmed 出版商
产品信息
SKU号 :
EK0469-PR
产品名称 :
Monkey primate NGF/NGF Beta ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
描述 :
Monkey primate NGF/NGF Beta ELISA Kit PicoKine® (96 Tests). Quantitate Monkey NGF in cell culture supernatants and serum. Sensitivity: 1pg/ml.
反应物种 :
Monkey
应用 :
酶联免疫吸附测定
基因名称 :
神经生长因子
UniProt数据库编号 :
P01138
免疫原 :
Expression system for standard: NS0; Immunogen sequence: S122-A241
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
15.6 pg/ml - 1,000 pg/ml
敏感性 :
<1 pg/ml
样品类型 :
cell culture supernatants and serum
Capture/Detection Antibodies :
单克隆抗体来自小鼠, 多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
β神经生长因子
同义词 :
β神经生长因子;乙神经生长因子;神经生长因子;NGFB;
蛋白名 :
β神经生长因子
分子量 :
26959分子量
Protein Function :
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
Subcellular Localization :
Secreted.
Sequence Similarities :
Belongs to the NGF-beta family.
背景 :
Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurones. NGF activity isolated from the male monkey primate submaxillary gland (MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight (Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF. NGF, which is expressed by inflammatory cells and effects changes that lead to increased neural responsiveness, could be a pivotal mediator in allergic rhinitis. The standard product used in this kit is monkey primate 2.5S NGF, which is a dimmer linking with two polypeptide chains of 120 amino acids.
研究种类 :
Growth And Development, Mesenchymal Stem Cells, Neural Stem Cells, Neurology Process, Neuroscience, Stem Cells, Surface Molecules
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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