武汉博士德生物工程有限公司

ELISA/assay

Human NGF/NGF Beta PicoKine ELISA Kit

EK0469

96 wells/kit

260美元

EK0469

Human NGF/NGF Beta PicoKine ELISA Kit

260美元

Expression system for standard: NSO; Immunogen sequence: S122-A241

Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human NGF/NGF beta

96 wells/kit

人类

酶联免疫吸附测定

Nerve growth factor(NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurones. NGF activity isolated from the male mouse submaxillary gland(MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight(Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF. NGF, which is expressed by inflammatory cells and effects changes that lead to increased neural responsiveness, could be a pivotal mediator in allergic rhinitis. The standard product used in this kit is human 2.5S NGF, which is a dimmer linking with two polypeptide chains of 120 amino acids.

There is no detectable cross-reactivity with other relevant proteins.

β神经生长因子

神经生长因子

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).

β神经生长因子

neuroscience neurology process growth and development neurotrophins stem cells neural stem cells surface molecules mesenchymal stem cells

Belongs to the NGF-beta family.

Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Secreted.

β神经生长因子;乙神经生长因子;神经生长因子;NGFB;

P01138