ELISA/assay

Human sL-Selectin PicoKine ELISA Kit

EK0503

96 wells/kit

350美元

Human sL-Selectin PicoKine ELISA Kit

350美元

Expression system for standard: NSO; Immunogen sequence: W39-N332

Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human sL-Selectin

96 wells/kit

人类

酶联免疫吸附测定

L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17.SELL(L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins.1L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point2.

There is no detectable cross-reactivity with other relevant proteins.

淋巴细胞型选择素

SELL

Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.

淋巴细胞型选择素

cardiovascular blood immunology adaptive immunity t cells stem cells hematopoietic progenitors lymphoid t lymphocytic lineage myeloid neutrophil lineage regulatory t cells

Belongs to the selectin/LECAM family.

Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Membrane; Single-pass type I membrane protein.

L-selectin;CD62 antigen-like family member L;Leukocyte adhesion molecule 1;LAM-1;Leukocyte surface antigen Leu-8;Leukocyte-endothelial cell adhesion molecule 1;LECAM1;Lymph node homing receptor;TQ1;gp90-MEL;CD62L;SELL;LNHR, LYAM1;

Expressed in B-cell lines and T-lymphocytes.

P14151