产品简要
信息索取 :
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Human P-Selectin PicoKine ELISA Kit
目录 :
EK0505
规格 :
96 wells/kit
价格 :
300美元
产品信息
SKU号 :
EK0505
名称 :
Human P-Selectin PicoKine ELISA Kit
价格 :
300美元
免疫原 :
Expression system for standard: NSO; Immunogen sequence: W42-A771
描述 :
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human P-Selectin
规格 :
96 wells/kit
反应物种 :
人类
应用 :
酶联免疫吸附测定
背景 :
P-selectin, also called GMP-140, CD62, or selectin P, is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is stored in secretory granules and expressed at the plasma membrane after cell activation. It is known to play an important role in atherosclerosis. The major ligand for P-selectin on leukocytes is P-selectin glycoprotein ligand-1(PSGL-1). The standard product used in this kit is recombinant human P-Selectin, excluding intercellular P-Selectin and transmembrane domain. It has 730 amino acids sequence with the molecular mass of 80 KDa.
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
基因全称 :
血小板型选择素
基因名称 :
SELP
protein function :
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.
蛋白名 :
血小板型选择素
研究种类 :
SELP
sequence similarities :
Belongs to the selectin/LECAM family.
储存 :
Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
subcellular localization :
Membrane; Single-pass type I membrane protein.
同义词 :
P-selectin;CD62 antigen-like family member P;Granule membrane protein 140;GMP-140;Leukocyte-endothelial cell adhesion molecule 3;LECAM3;Platelet activation dependent granule-external membrane protein;PADGEM;CD62P;SELP;GMRP, GRMP;
组织特异性 :
Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
UniProt数据库编号 :
P16109
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.boster.com.cn
925.485.4527
公司总部: 美国
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