ELISA/assay

Mouse TNFsR I ELISA Kit PicoKine®

EK0529

1

Mouse TNFsR I ELISA Kit PicoKine®

小鼠tnfr1

Picokine ELISA Kits

肿瘤坏死因子受体超家族成员1A

369

15.6 pg/ml - 1,000 pg/ml

Mouse TNFsR I ELISA Kit PicoKine (96 Tests). Quantitate Mouse Tnfrsf1a in cell culture supernatants and serum. Sensitivity: 10pg/ml.

Mouse TNFsR I ELISA Kit PicoKine (96 Tests). Quantitate Mouse Tnfrsf1a in cell culture supernatants and serum. Sensitivity: 10pg/ml.

96 wells/kit, with removable strips.

P25118

Expression system for standard: NS0; Immunogen sequence: L30-A212

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

There is no detectable cross-reactivity with other relevant proteins.

<10 pg/ml

10 ng/tube

cell culture supernatants and serum.

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小鼠

/antibody/ek0529-ELISA-mouse-tnfsr-i-picokine-elisa-kit.png

Mouse TNFR1 PicoKine ELISA Kit standard curve

Concentration (pg/ml) 0 15.6 31.2 62.5 125 250 500 1000 O.D. 0.036 0.110 0.215 0.442 0.822 1.328 1.876 2.152

9/10/15 13:26

3/2/22 2:55

Mouse TNFsR I ELISA Kit Price PicoKine® BosterBio

Mouse TNFR1 ELISA Kit, p65/TNF Receptor I ELISA, Bosterbio High Sensitivity

Mouse TNFsR I ELISA Kit PicoKine (96 Tests). Quantitate Mouse Tnfrsf1a in cell culture supernatants and serum. Sensitivity: 10pg/ml.

100

1,000 pg/ml, 500 pg/ml, 250 pg/ml, 125 pg/ml, 62.5 pg/ml, 31.2 pg/ml, 15.6 pg/ml

Tumor necrosis factor receptor 1 (TNFR1), also known as tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) and CD120a, is a ubiquitous membrane receptor that binds tumor necrosis factor-alpha (TNF alpha). The protein encoded by this gene is a member of the tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. And this protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor.

信号转导

Tumor necrosis factor receptor superfamily member 1A;Tumor necrosis factor receptor 1;TNF-R1;Tumor necrosis factor receptor type I;TNF-RI;TNFR-I;p55;p60;CD120a;Tnfrsf1a;Tnfr-1, Tnfr1;

Tumor necrosis factor receptor superfamily member 1A

50130分子量

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis (By similarity).

Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane ; Single-pass type I membrane protein .

Tumor necrosis factor receptor superfamily member 1A

Intra-Assay Precision Inter-Assay Precision Sample 1 2 3 1 2 3 n 16 16 16 24 24 24 Mean (pg/ml) 35 224 437 37 204 459 Standard deviation 1.5 13.88 27.22 1.7 18%2 27.08 CV (%) 4.3% 6.2% 5.5% 4.6% 8% 5.9%

Lots Lot 1 (pg/ml) Lot 2 (pg/ml) Lot 3 (pg/ml) Lot 4 (pg/ml) Mean (pg/ml) Standard Deviation CV (%) Sample 1 35 39 42 39 38 2.48 6.5% Sample 2 224 227 240 237 232 6.67 2.8% Sample 3 495 438 426 477 459 28.06 6.1% *number of samples for each test n=16.

15-25min

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