产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Mouse VEGFR3/FLT4 ELISA Kit PicoKine®
目录 :
EK0546
图像
图像 1 :
武汉博士德生物工程有限公司 EK0546 图像 1
Mouse VEGFR3/FLT4 PicoKine ELISA Kit standard curve
产品信息
SKU号 :
EK0546
状态 :
1
名称 :
Mouse VEGFR3/FLT4 ELISA Kit PicoKine®
url key :
小鼠vegfr3
产品种类 :
Picokine ELISA Kits
基因名称 :
FLT4
价格 :
369
试验范围 :
156 pg/ml - 10,000 pg/ml
描述 :
Mouse VEGFR3/FLT4 ELISA Kit PicoKine (96 Tests). Quantitate Mouse Flt4 in cell culture supernatants and serum. Sensitivity: 10pg/ml.
short description :
Mouse VEGFR3/FLT4 ELISA Kit PicoKine (96 Tests). Quantitate Mouse Flt4 in cell culture supernatants and serum. Sensitivity: 10pg/ml.
规格 :
96 wells/kit, with removable strips.
UniProt数据库编号 :
P35917
免疫原 :
Expression system for standard: NS0; Immunogen sequence: Y25?D770
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
敏感性 :
<10 pg/ml
kit components :
10 ng/tube
样品类型 :
cell culture supernatants and serum.
应用细节 :
Dilution ratio of 1:1, concentration in serum is around 1ng/ml
应用 :
酶联免疫吸附测定
反应物种 :
小鼠
images :
/antibody/ek0546-2-ELISA-mouse-vegfr3-flt4-picokine-elisa-kit.jpg
图像标记 :
Mouse VEGFR3/FLT4 PicoKine ELISA Kit standard curve
样本数据 :
Concentration (pg/ml) 0 156 312 625 125000 25000 5000 10000 O.D. 0.016 0.078 0.128 0.200 0.412 0.853 1.434 2.097
created at :
9/17/14 11:44
updated at :
3/2/22 2:55
meta title :
Mouse VEGFR3/FLT4 ELISA Kit Price PicoKine® BosterBio
meta keyword :
Mouse VEGFR3/FLT4 ELISA Kit, Bosterbio High Sensitivity
meta description :
Mouse VEGFR3/FLT4 ELISA Kit PicoKine (96 Tests). Quantitate Mouse Flt4 in cell culture supernatants and serum. Sensitivity: 10pg/ml.
rating value :
97.4
assay procedure step 1 :
10,000 pg/ml, 5,000 pg/ml, 2,500 pg/ml, 1,250 pg/ml, 625 pg/ml, 312 pg/ml, 156 pg/ml
背景 :
Fms-related tyrosine kinase 4, also known as FLT4 or VEGFR3, is a protein which in humans is encoded by the FLT4 gene. It is mapped to 5q35.3. This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. FLT4 has an essential role in the development of the embryonic cardiovascular system before the emergence of the lymphatic vessels. It has been found that FLT4, which provides proangiogenic signaling when expressed on endothelium, may also have antiangiogenic properties when expressed at an avascular site by nonendothelial cells. FLT4 is also regarded as a regulator of vascular network formation.
研究种类 :
Angiogenesis,Cardiovascular,Growth Factors,Protein Phosphorylation,Receptor Tyrosine Kinases,Signal Transduction,Tyrosine Kinases
同义词 :
Vascular endothelial growth factor receptor 3;VEGFR-3;2.7.10.1;Fms-like tyrosine kinase 4;FLT-4;Tyrosine-protein kinase receptor FLT4;Flt4;Flt-4, Vegfr3;
基因全称 :
血管内皮生长因子受体3
分子量 :
153016分子量
protein function :
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. Mediates activation of the MAPK1/ERK2, MAPK3/ERK1 signaling pathway, of MAPK8 and the JUN signaling pathway, and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr- 185', and of AKT1 at 'Ser-473'.
subcellular localization :
Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Nucleus . Ligand-mediated autophosphorylation leads to rapid internalization.
组织特异性 :
Expressed in adult lung and liver, and in fetal liver, brain, intestine and placenta.
蛋白名 :
血管内皮生长因子受体3
sequence similarities :
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
intra inter assay cv :
Intra-Assay Precision Inter-Assay Precision Sample 1 2 3 1 2 3 n 16 16 16 24 24 24 Mean (pg/ml) 287 1392 5844 306 1363 5406 Standard deviation 22.38 87.69 344.79 29.07 99.49 389.23 CV (%) 7.8% 7.3%% 5.9% 9.5% 7.3% 7.2%
再现性 :
Lots Lot 1 (pg/ml) Lot 2 (pg/ml) Lot 3 (pg/ml) Lot 4 (pg/ml) Mean (pg/ml) Standard Deviation CV (%) Sample 1 287 282 308 309 296 12.13 4% Sample 2 1392 1474 1350 1411 1406 44.66 3.1% Sample 3 5844 5515 6505 5591 5863 389.74 6.6% *number of samples for each test n=16.
tmb incubation time :
15-25min
principle :
单克隆抗体来自大鼠多克隆抗体来自山羊
template :
酶联免疫吸附试剂盒
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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