ELISA/assay

Dog N-Cadherin-2 CDH2 CD325 ELISA Kit PicoKine®

EK0669-CN

96 wells/kit, with removable strips.

369美元

Dog N-Cadherin-2 CDH2 CD325 ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Dog N-Cadherin-2 CDH2 CD325 ELISA Kit PicoKine® (96 Tests). Quantitate Dog CDH2 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml.

狗

酶联免疫吸附测定

CDH2

P19022

Expression system for standard: NS0; Immunogen sequence: D160-A724

There is no detectable cross-reactivity with other relevant proteins.

156 pg/ml - 10,000 pg/ml

<20 pg/ml

cell culture supernatants, serum and plasma (heparin, EDTA)

单克隆抗体来自小鼠, 多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

钙粘蛋白2

Cadherin-2;CDw325;Neural cadherin;N-cadherin;CD325;CDH2;CDHN, NCAD;

钙粘蛋白2

99809分子量

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).

Cell membrane; Single-pass type I membrane protein.

Cadherin-2 (CDH2), also known as neural cadherin (NCAD), is a protein that in Dog Canineas is encoded by the CDH2 gene. It is a classical cadherin from the cadherin superfamily. This gene is mapped to 18q12.1. Cadherin-2 is expressed in the brain, skeletal and cardiac muscle. Cadherin-2 is commonly found in cancer cells and provides a mechanism for transendothelial migration. It is a calcium dependent cell-cell adhesion glycoprotein comprising five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Cadherins, Cell Adhesion, Cytoskeleton / Ecm, Signal Transduction