产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Human Cystatin C PicoKine ELISA Kit
目录 :
EK0678
规格 :
96 wells/kit
价格 :
400美元
产品信息
SKU号 :
EK0678
名称 :
Human Cystatin C PicoKine ELISA Kit
价格 :
400美元
免疫原 :
Expression system for standard: NSO; Immunogen sequence: M1-A146
描述 :
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Cystatin C
规格 :
96 wells/kit
反应物种 :
人类
应用 :
酶联免疫吸附测定
背景 :
Cystatin C or cystatin 3(formerly gamma trace, post-gamma-globulin or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, was originally described as a constituent of normal cerebrospinal fluid(CSF) and of urine from patients with renal failure.1 Cystatin 3 has a low molecular weight(approximately 13.3 kilodaltons), and it is removed from the bloodstream by glomerular filtration in the kidneys. In humans, all cells with a nucleus(cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and bodily fluids. Cystatin C, which belongs to the type II cystatin gene family, is a potent inhibitor of lysosomal proteinases2(enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases3(it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Moreover, cystatin C is involved in network reorganization in the epileptic dentate gyrus.4
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
基因全称 :
胱蛋白C
基因名称 :
CST3
protein function :
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
蛋白名 :
胱蛋白C
研究种类 :
tags & cell markers cell type markers tumor associated cell biology apoptosis intracellular caspases etc inhibitors stem cells neural stem cells extracellular cardiovascular atherosclerosis thrombosis
储存 :
Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
subcellular localization :
Secreted .
同义词 :
Cystatin-C;Cystatin-3;Gamma-trace;Neuroendocrine basic polypeptide;Post-gamma-globulin;CST3;
组织特异性 :
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
UniProt数据库编号 :
P01034
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.boster.com.cn
925.485.4527
公司总部: 美国
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