ELISA/assay

Human CD163 / M130 ELISA Kit PicoKine®

EK0715

1

Human CD163 / M130 ELISA Kit PicoKine®

人类cd163

Picokine ELISA Kits

CD163

369

1.56 ng/ml - 100 ng/ml

Human CD163 / M130 ELISA Kit PicoKine (96 Tests). Quantitate Human CD163 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 150pg/ml.

Human CD163 / M130 ELISA Kit PicoKine (96 Tests). Quantitate Human CD163 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 150pg/ml.

96 wells/kit, with removable strips.

Q86VB7

Expression system for standard: NS0; Immunogen sequence: G41-S1045

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

There is no detectable cross-reactivity with other relevant proteins.

<150 pg/ml

100 ng/tube

cell culture supernatants, serum and plasma (heparin).

Dilution ratio of 1:40, concentration in serum is around 500ng/ml

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人类

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Human CD163 PicoKine ELISA Kit standard curve

Concentration (ng/ml) 0 1.56 3.12 6.25 12.5 25 50 100 O.D. 0.012 0.046 0.096 0.205 0.449 0.973 1.864 2.469

7/13/14 1:17

3/2/22 2:54

Featured Product . Fast ELISA kit now available: Boster is proud to announce the newest Picokine Fast ELISA kits. Now you can perform what used to be 4+ hour ELISA assay in under 1.5 hours. Available for Human CD163 / M130 PicoKine Fast ELISA Kit and many others.

Human CD163 / M130 ELISA Kit Price PicoKine® BosterBio

Human CD163 ELISA Kit, C163A ELISA Kit, Bosterbio High Sensitivity

Human CD163 / M130 ELISA Kit PicoKine (96 Tests). Quantitate Human CD163 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 150pg/ml.

99.4

肝素

100 ng/ml, 50 ng/ml, 25 ng/ml, 12.5 ng/ml, 6.25 ng/ml, 3.13 ng/ml, 1.56 ng/ml

CD163 (Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. It has also been shown to mark cells of monocyte/macrophage lineage. CD163, a member of the scavenger receptor cysteine-rich (SRCR) superfamily, is exclusively expressed by monocytes and macrophages. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, CD163 gene was mapped the to chromosome 12p13.3. CD163 is upregulated in a large range of diseases inflammatory diseases including type 2 diabetes, macrophage activation sickness, Tangier's disease, reumatoid arthritis etc.

sc 33560 sc 58965 sc 33715 sc 18796 sc 33559 sc 20066 sc 18794

Atherosclerosis,Cardiovascular,Cell Type Markers,Immunology,Innate Immunity,Macrophage / Inflamm.,Vascular Inflammation

Scavenger receptor cysteine-rich type 1 protein M130;Hemoglobin scavenger receptor;CD163;Soluble CD163;sCD163;CD163;M130;

Scavenger receptor cysteine-rich type 1 protein M130

125451分子量

Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.

Soluble CD163: Secreted.

Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen, cortical macrophages in the thymus, resident bone marrow macrophages and meningeal macrophages of the central nervous system. Expressed also in blood. Isoform 1 is the lowest abundant in the blood. Isoform 2 is the lowest abundant in the liver and the spleen. Isoform 3 is the predominant isoform detected in the blood.

Scavenger receptor cysteine-rich type 1 protein M130

含9 SRCR区域

Intra-Assay Precision Inter-Assay Precision Sample 1 2 3 1 2 3 n 16 16 16 24 24 24 Mean (pg/ml) 3520 11456 44674 3368 11294 48653 Standard deviation 144.32 526.97 3037.82 195.34 632.46 3357.05 CV (%) 4.1% 4.6% 6.8% 5.8% 5.6% 6.9%

Lots Lot 1 (pg/ml) Lot 2 (pg/ml) Lot 3 (pg/ml) Lot 4 (pg/ml) Mean (pg/ml) Standard Deviation CV (%) Sample 1 3520 3403 3222 3050 3298 178.59 5.4% Sample 2 11456 11119 13238 12078 11972 807.44 6.7% Sample 3 44674 42932 42302 44756 43666 1072.77 2.4% *number of samples for each test n=16.

15-25min

单克隆抗体来自小鼠多克隆抗体来自山羊

24548423, 25392926, 25156085, 24978196

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