Human EPCAM/Trop1 ELISA Kit PicoKine¬Æ | 武汉博士德生物工程有限公司 EK0755 产品信息

产品简要

公司名称 :

武汉博士德生物工程有限公司

产品类型 :

ELISA/assay

产品名称 :

Human EPCAM/Trop1 ELISA Kit PicoKine¬Æ

EK0755

更多信息或购买 :

武汉博士德生物工程有限公司产品网页

图像

图像 1 :

Human EPCAM PicoKine ELISA Kit standard curve

产品信息

SKU号 :

EK0755

状态 :

名称 :

Human EPCAM/Trop1 ELISA Kit PicoKine¬Æ

url key :

human-epcam-picokine-trade-elisa-kit-ek0755-boster

产品种类 :

Picokine ELISA Kits

基因名称 :

EPCAM

价格 :

369

试验范围 :

15.6 pg/ml - 1,000 pg/ml

描述 :

Human EPCAM/Trop1 ELISA Kit PicoKine (96 Tests). Quantitate Human EPCAM in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

short description :

Human EPCAM/Trop1 ELISA Kit PicoKine (96 Tests). Quantitate Human EPCAM in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

规格 :

96 wells/kit, with removable strips.

UniProt数据库编号 :

P16422

免疫原 :

Expression system for standard: NS0; Immunogen sequence: Q24-K265

储存 :

Store at 4¬∞C for 6 months, at -20¬∞C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

交叉活性 :

There is no detectable cross-reactivity with other relevant proteins.

敏感性 :

<10 pg/ml

kit components :

10 ng/tube

样品类型 :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

应用细节 :

Dilution ratio of 1:1, concentration in serum is 200-400pg/ml

应用 :

酶联免疫吸附测定

反应物种 :

人类

images :

/e/k/ek0755_1.png

图像标记 :

Human EPCAM PicoKine ELISA Kit standard curve

样本数据 :

Concentration (pg/ml) 0 15.6 31.2 62.5 125 250 500 1000 O.D. 0.008 0.047 0.111 0.216 0.485 1.026 1.682 2.044

created at :

10/19/15 21:13

updated at :

3/2/22 2:55

description before attributes :

Featured Product . Fast ELISA kit now available: Boster is proud to announce the newest Picokine Fast ELISA kits. Now you can perform what used to be 4+ hour ELISA assay in under 1.5 hours. Available for Human EPCAM/Trop1 PicoKine Fast ELISA Kit and many others.

meta title :

Human EPCAM/Trop1 ELISA Kit Price PicoKine¬Æ BosterBio

meta keyword :

Human EPCAM ELISA Kit, CD326 ELISA Kit, Bosterbio High Sensitivity

meta description :

Human EPCAM/Trop1 ELISA Kit PicoKine (96 Tests). Quantitate Human EPCAM in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

rating value :

99.2

anticoagulant :

肝素或乙二胺四乙酸

assay procedure step 1 :

1,000 pg/ml, 500 pg/ml, 250 pg/ml, 125 pg/ml, 62.5 pg/ml, 31.2 pg/ml, 15.6 pg/ml

背景 :

Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. Also it is involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since it is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.

研究种类 :

Cell Type Markers,Tags & Cell Markers,Tumor Associated

同义词 :

Epithelial cell adhesion molecule;Ep-CAM;Adenocarcinoma-associated antigen;Cell surface glycoprotein Trop-1;Epithelial cell surface antigen;Epithelial glycoprotein;EGP;Epithelial glycoprotein 314;EGP314;hEGP314;KS 1/4 antigen;KSA;Major gastrointestinal tumor-associated protein GA733-2;Tumor-associated calcium signal transducer 1;CD326;EPCAM;GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1;

基因全称 :

上皮细胞粘连分子

分子量 :

34932分子量

protein function :

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

subcellular localization :

Lateral cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Colocalizes with CLDN7 at the lateral cell membrane and tight junction.

组织特异性 :

Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.

蛋白名 :

上皮细胞粘连分子

sequence similarities :

Belongs to the EPCAM family. Contains 1 thyroglobulin type-1 domain.

intra inter assay cv :

Intra-Assay Precision Inter-Assay Precision Sample 1 2 3 1 2 3 n 16 16 16 24 24 24 Mean (pg/ml) 38 143 444 35 150 444 Standard deviation 1.63 6 33.74 1.82 7.5 37.29 CV (%) 4.3% 4.2% 7.6% 5.2% 5% 8.4%

再现性 :

Lots Lot 1 (pg/ml) Lot 2 (pg/ml) Lot 3 (pg/ml) Lot 4 (pg/ml) Mean (pg/ml) Standard Deviation CV (%) Sample 1 38 35 32 35 35 2.12 6% Sample 2 143 161 140 157 150 8.92 5.9% Sample 3 444 418 452 413 431 16.58 3.8% *number of samples for each test n=16.

tmb incubation time :

15-25min

principle :

单克隆抗体来自小鼠多克隆抗体来自山羊

template :

酶联免疫吸附试剂盒

更多信息或购买 :

武汉博士德生物工程有限公司产品网页

公司信息