产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Human P53 PicoKine ELISA Kit
目录 :
EK0895
规格 :
96 wells/kit
价格 :
420美元
产品信息
SKU号 :
EK0895
名称 :
Human P53 PicoKine ELISA Kit
价格 :
420美元
免疫原 :
Expression system for standard: NSO; Immunogen sequence: M1-D393
描述 :
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human P53
规格 :
96 wells/kit
反应物种 :
人类
应用 :
酶联免疫吸附测定
背景 :
P53(also known as protein 53 or tumor protein 53), is a tumor suppressor protein that in humans is encoded by the TP53 gene. The human P53 gene is mapped to chromosome 17. Human p53 is 393 amino acids long and has seven domains. It runs as a 53-kilodalton(kDa) protein on SDS-PAGE. The pattern of p53 splicing was specific for brain areas and for individuals. And human kidney and heart expressed only full-length p53. It has played a vital role in conserving stability by preventing genome mutation.
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
基因全称 :
Cellular tumor antigen p53
基因名称 :
TP53;TP53
protein function :
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
蛋白名 :
Cellular tumor antigen p53
研究种类 :
cell biology apoptosis intracellular p53 pathway
储存 :
Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
subcellular localization :
Cytoplasm. Nucleus.
同义词 :
Cellular tumor antigen p53 ;TP53 ;
UniProt数据库编号 :
K7PPA8
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.boster.com.cn
925.485.4527
公司总部: 美国
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